[Determination of critical kanamycin concentration for Mycobacterium tuberculosis in the MGIT Bactec 960 system]

V N Stepanshina; S A Popov; N A Aparina; R I Mironova; T N Mukhina; A V Nizova; N V Maĭskaia; O G Nikolaeva; A G Bogun; S A Blagodatskikh; I G Shemiakin; P Cegelski

[Determination of critical kanamycin concentration for Mycobacterium tuberculosis in the MGIT Bactec 960 system]

Tuberk Biolezni Legkih. 2009:(12):71-8.

[Article in Russian]

Authors

V N Stepanshina, S A Popov, N A Aparina, R I Mironova, T N Mukhina, A V Nizova, N V Maĭskaia, O G Nikolaeva, A G Bogun, S A Blagodatskikh, I G Shemiakin, P Cegelski

PMID: 20095377

Abstract

The critical concentration of canamycin for the MGIT Bactec 960 system, which has been determined on a panel of the tho--roughly characterized genetically heterogeneous clinical Mycobacterium tuberculosis isolated in the Central Region of Russia, is equal to 1.25 microg/ml.

Publication types

Comparative Study
English Abstract

MeSH terms

Anti-Bacterial Agents / administration & dosage*
DNA, Bacterial / analysis*
Dose-Response Relationship, Drug
Equipment Design
Humans
Kanamycin / administration & dosage*
Microbial Sensitivity Tests / instrumentation*
Mycobacterium tuberculosis / drug effects*
Mycobacterium tuberculosis / genetics
Tuberculosis, Pulmonary / drug therapy*
Tuberculosis, Pulmonary / microbiology

Substances

Anti-Bacterial Agents
DNA, Bacterial
Kanamycin