The use of second-harmonic generation to study diffusion through films under a liquid phase

Chemphyschem. 2010 Mar 15;11(4):870-4. doi: 10.1002/cphc.200900874.

Abstract

Knowledge of the diffusion of chemicals through buried films is important for a wide variety of systems--from sensing to drug delivery. Herein, we show that second-harmonic generation (SHG) can be used to follow the diffusion through a thin film buried under a liquid in situ. More specifically, the diffusion of 4-(4-diethylaminostyryl)-1-methylpyridinium iodide through zeolite precursor films of different thickness is followed. The diffusion coefficients are calculated according to Fick's law.