L-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination

J Antibiot (Tokyo). 1991 Feb;44(2):249-54. doi: 10.7164/antibiotics.44.249.
No abstract available

MeSH terms

  • Chromatography, Gel
  • Complement C5a / antagonists & inhibitors*
  • Fermentation
  • Humans
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Conformation
  • Molecular Structure
  • Peptides, Cyclic / biosynthesis*
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / isolation & purification
  • Streptomyces / metabolism*
  • X-Ray Diffraction

Substances

  • Peptides, Cyclic
  • PD 124966
  • Complement C5a