Anti-N-methyl-D-aspartate-receptor encephalitis in a four-year-old girl

J Pediatr. 2010 Feb;156(2):332-4. doi: 10.1016/j.jpeds.2009.07.057.

Abstract

Anti-N-methyl-D-aspartate-receptor encephalitis is a recently identified autoimmune disorder. We report on a 4-year-old girl presenting with seizures after nonspecific viral-like symptoms, progressing to severe aphasia, upper limb dyskinesias, fluctuation in consciousness, and inability to walk. Anti-N-methyl-D-aspartate-receptor encephalitis should be included in the differential diagnosis of acute/subacute encephalitis in children.

Publication types

  • Case Reports

MeSH terms

  • Aphasia / etiology
  • Autoimmune Diseases of the Nervous System* / diagnosis
  • Autoimmune Diseases of the Nervous System* / therapy
  • Child, Preschool
  • Cognition Disorders / etiology
  • Electroencephalography
  • Encephalitis / diagnosis
  • Encephalitis / immunology*
  • Encephalitis / therapy
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunologic Factors / therapeutic use
  • Magnetic Resonance Imaging
  • Receptors, N-Methyl-D-Aspartate / immunology*
  • Seizures / etiology

Substances

  • Immunoglobulins, Intravenous
  • Immunologic Factors
  • Receptors, N-Methyl-D-Aspartate