Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

ChemMedChem. 2010 Mar 1;5(3):357-60. doi: 10.1002/cmdc.200900472.
No abstract available

MeSH terms

  • Amidohydrolases / antagonists & inhibitors*
  • Amidohydrolases / metabolism*
  • Animals
  • Cannabinoid Receptor Modulators / metabolism
  • Carbamates / administration & dosage
  • Carbamates / chemistry*
  • Carbamates / metabolism
  • Carbamates / pharmacology*
  • Endocannabinoids
  • Humans
  • Mice
  • Plasma / metabolism
  • Rats
  • Structure-Activity Relationship

Substances

  • Cannabinoid Receptor Modulators
  • Carbamates
  • Endocannabinoids
  • Amidohydrolases
  • fatty-acid amide hydrolase