Objective: To isolate the active component from Dioscorea cirrhosa Lour and test its activity in lowering blood pressure.
Methods: The serial components were obtained from the total extract, ligroin extract, ethyl acetate, n-butyl alcohol extract and water extract. The isolated active components were administered in rats via the common carotid artery canulation and tail vein injection to test their effects on blood pressure.
Results: The component A isolated and purified from normal butanol showed obvious effect in lowering the blood pressure of rats.
Conclusion: The isolated active component from Dioscorea cirrhosa Lour possesses obvious blood pressure-lowering activity.