A Fluorescent Hydrogen Peroxide Probe Based on a 'Click' Modified Coumarin Fluorophore

Tetrahedron Lett. 2010 Feb 24;51(8):1152-1154. doi: 10.1016/j.tetlet.2009.12.049.

Abstract

Herein a water-soluble 'click' modified coumarin-based fluorescent probe for hydrogen peroxide is reported. This probe shows significant intensity increases (up to 5 fold) in near-green fluorescence upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species.