Resolving the controversy about N-cadherin and hematopoietic stem cells

Cell Stem Cell. 2010 Mar 5;6(3):199-202. doi: 10.1016/j.stem.2010.02.007.

Abstract

Discrepancies in published results about the role of N-cadherin in hematopoietic stem cells have led to confusion in the field. Attempting to settle the disagreements and reach a consensus, we undertook a collective discussion approach. This process clarified a number of issues but left some questions still unresolved.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cadherins / genetics
  • Cadherins / metabolism*
  • Cell Adhesion
  • Cell Communication
  • Hematopoietic Stem Cells / cytology
  • Hematopoietic Stem Cells / metabolism*
  • Mice
  • Stem Cell Niche / cytology
  • Stem Cell Niche / metabolism

Substances

  • Cadherins