Antimicrobial susceptibilities of health care-associated and community-associated strains of methicillin-resistant Staphylococcus aureus from hospitalized patients in Canada, 1995 to 2008

Antimicrob Agents Chemother. 2010 May;54(5):2265-8. doi: 10.1128/AAC.01717-09. Epub 2010 Mar 15.

Abstract

We determined the in vitro antimicrobial susceptibilities of 7,942 methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from patients hospitalized in 48 Canadian hospitals from 1995 to 2008. Regional variations in susceptibilities were identified. The dissemination of community-associated strains in Canada appears to have contributed to increased susceptibility of MRSA to several non-beta-lactam antimicrobial agents in the past decade. Reduced susceptibility to glycopeptides was not identified.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Canada / epidemiology
  • Community-Acquired Infections / drug therapy*
  • Community-Acquired Infections / epidemiology
  • Cross Infection / drug therapy*
  • Cross Infection / epidemiology
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Methicillin Resistance*
  • Methicillin-Resistant Staphylococcus aureus / drug effects*
  • Public Health / statistics & numerical data
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / epidemiology

Substances

  • Anti-Bacterial Agents