Abstract
In the last years much attention has been given to the implementation of the so-called targeted drugs. One of the targets of tumours is the vasculature and this has led to the development of anti-angiogenic drugs. In lung cancer the use of these drugs has resulted in both positive and negative studies. In this paper the pros and cons are presented. We hope that this information will help the physician in making a proper treatment choice.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Angiogenesis Inhibitors / economics
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Angiogenesis Inhibitors / therapeutic use*
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Antibodies, Monoclonal / economics
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Antibodies, Monoclonal / therapeutic use
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Antibodies, Monoclonal, Humanized
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bevacizumab
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Carboplatin / administration & dosage
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Carcinoma, Non-Small-Cell Lung / blood supply
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Carcinoma, Non-Small-Cell Lung / drug therapy*
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Carcinoma, Non-Small-Cell Lung / metabolism
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Cost-Benefit Analysis
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Humans
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Lung Neoplasms / blood supply
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Lung Neoplasms / drug therapy*
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Lung Neoplasms / metabolism
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Paclitaxel / administration & dosage
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Treatment Outcome
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Vascular Endothelial Growth Factor A / metabolism
Substances
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Angiogenesis Inhibitors
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Vascular Endothelial Growth Factor A
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Bevacizumab
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Carboplatin
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Paclitaxel