[Component-based diagnostic approach. Detection of sensitization to lipid transfer proteins in food allergy]

Abstract

Sensitization to lipid transfer proteins (LTPs), a pan-allergen in plants, causes severe anaphylactic reactions to foods, especially in the Mediterranean area. A component-based diagnostic approach identified the peach LTP Pru p 3 as a major allergen. We present the case of a 30-year-old LTP-sensitized Spanish woman with a history of severe anaphylactic reaction to grapes, apple and cauliflower in which the detection of specific IgE against the recombinant protein Pru p 3 led to the diagnosis.