Abstract
Covalent embedding of a (eta(6)-arene) ruthenium(II) complex into the protein papain gives rise to a metalloenzyme displaying a catalytic efficiency for a Lewis acid-mediated catalysed Diels-Alder reaction enhanced by two orders of magnitude in water.
MeSH terms
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Acids / chemistry*
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Catalysis
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Coordination Complexes / chemistry*
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Crystallography, X-Ray
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Kinetics
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Molecular Conformation
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Papain / chemistry*
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Ruthenium / chemistry*
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Water / chemistry*
Substances
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Acids
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Coordination Complexes
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Water
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Ruthenium
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Papain