Abstract
We conducted a pilot randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children. Treatment was successful in 7 of 7 children treated with trimethoprim-sulfamethoxazole and 5 of 6 treated with benzathine penicillin. Trimethoprim-sulfamethoxazole achieved microbiological clearance and healing of sores from which beta-hemolytic streptococci and community-associated methicillin-resistant Staphylococcus aureus were initially cultured.
Publication types
-
Comparative Study
-
Randomized Controlled Trial
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Administration, Oral
-
Adolescent
-
Anti-Infective Agents / administration & dosage
-
Anti-Infective Agents / therapeutic use*
-
Child
-
Child, Preschool
-
Female
-
Humans
-
Impetigo / drug therapy*
-
Impetigo / microbiology
-
Infant
-
Injections, Intramuscular
-
Male
-
Methicillin-Resistant Staphylococcus aureus
-
Northern Territory
-
Penicillin G Benzathine / administration & dosage
-
Penicillin G Benzathine / therapeutic use*
-
Pilot Projects
-
Streptococcus pyogenes
-
Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
-
Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use*
Substances
-
Anti-Infective Agents
-
Trimethoprim, Sulfamethoxazole Drug Combination
-
Penicillin G Benzathine