A highly sensitive and selective "signal-on" electrochemiluminescent biosensor for mercury

Xi Zhu; Lifeng Chen; Zhenyu Lin; Bin Qiu; Guonan Chen

doi:10.1039/b926319e

A highly sensitive and selective "signal-on" electrochemiluminescent biosensor for mercury

Chem Commun (Camb). 2010 May 14;46(18):3149-51. doi: 10.1039/b926319e. Epub 2010 Mar 11.

Authors

Xi Zhu¹, Lifeng Chen, Zhenyu Lin, Bin Qiu, Guonan Chen

Affiliation

¹ Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China.

PMID: 20424756
DOI: 10.1039/b926319e

Abstract

A highly sensitive and selective electrochemiluminescent biosensor was designed for mercury(ii) based on T-Hg(2+)-T complex by using Ru(bpy)(3)(2+)-doped silica nanoparticles (Ru-SNPs) to label the oligonucleotides in order to improve the sensitivity.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Base Pair Mismatch
Biosensing Techniques / instrumentation*
Biosensing Techniques / methods
DNA / metabolism
Luminescent Measurements / instrumentation*
Luminescent Measurements / methods
Mercury / analysis*
Mercury / metabolism
Sensitivity and Specificity
Thymidine / metabolism
Water Pollutants, Chemical / analysis*
Water Pollutants, Chemical / metabolism

Substances

Water Pollutants, Chemical
DNA
Mercury
Thymidine