Radiological findings of community-acquired methicillin-resistant and methicillin-susceptible Staphylococcus aureus pediatric pneumonia in Hawaii

Pediatr Radiol. 2010 Nov;40(11):1768-73. doi: 10.1007/s00247-010-1680-0. Epub 2010 May 14.

Abstract

Background: Community-acquired Staphylococcus aureus (CA-SA) infections are common among pediatric patients in Hawaii.

Objective: We wanted to characterize the radiological features of methicillin-susceptible (CA-MSSA) and methicillin-resistant (CA-MRSA) staphylococcal pneumonia in Hawaiian children.

Materials and methods: We retrospectively reviewed medical records and imaging studies of children with SA pneumonia identified from 1996 through 2007.

Results: Of 40 children, 26 (65%) had CA-MRSA pneumonia and 14 patients (35%) had CA-MSSA pneumonia. CA-MRSA patients were significantly younger than CA-MSSA patients (65% younger than 1 year vs. 36% older). In a majority (62%) of CA-MRSA patients, the consolidation was unilateral; in most of the CA-MSSA cases (79%), the consolidation was bilateral. Fifty percent of the patients with CA-MRSA and 21% of those with CA-MSSA had pneumatoceles (P = 0.1). CA-MRSA patients more commonly had pleural effusions (85% vs. 64% for CA-MSSA) and pleural thickening (50% vs. 36% for CA-MSSA).

Conclusion: This case series describes the radiologic characteristics of CA-MRSA and CA-MSSA pneumonia in children in a highly endemic area. We found that CA-MRSA pneumonias are unilateral in a majority of pediatric pneumonia cases, are more common in children 1 year or younger, and have higher rates of complications in comparison to CA-MSSA patients.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / epidemiology*
  • Female
  • Hawaii / epidemiology
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Methicillin Resistance*
  • Pneumonia, Staphylococcal / diagnostic imaging*
  • Pneumonia, Staphylococcal / drug therapy
  • Pneumonia, Staphylococcal / epidemiology*
  • Prevalence
  • Radiography, Thoracic / statistics & numerical data*
  • Risk Assessment
  • Risk Factors
  • Staphylococcus aureus / drug effects