A call to arms: interferons prepare bone marrow cells to battle peripheral infections

Jacob E Kohlmeier; David L Woodland

doi:10.1016/j.chom.2010.05.004

A call to arms: interferons prepare bone marrow cells to battle peripheral infections

Cell Host Microbe. 2010 May 20;7(5):336-7. doi: 10.1016/j.chom.2010.05.004.

Authors

Jacob E Kohlmeier¹, David L Woodland

Affiliation

¹ Trudeau Institute, 154 Algonquin Avenue, Saranac Lake, NY 12983, USA.

PMID: 20478533
DOI: 10.1016/j.chom.2010.05.004

Abstract

Viral infection leads to the rapid production of type I interferons within infected tissues. In this issue of Cell Host & Microbe, Hermesh et al. (2010) demonstrate that interferons produced following respiratory viral infection program leukocytes in the bone marrow to resist infection before trafficking to the lung.

Publication types

Comment
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't