Association study between GNB1L and three major mental disorders in Chinese Han populations

You Li; Qian Zhao; Ti Wang; Jie Liu; Junyan Li; Tao Li; Zhen Zeng; Guoyin Feng; Lin He; Yongyong Shi

doi:10.1016/j.psychres.2010.04.019

Association study between GNB1L and three major mental disorders in Chinese Han populations

Psychiatry Res. 2011 May 30;187(3):457-9. doi: 10.1016/j.psychres.2010.04.019. Epub 2010 Jun 9.

Authors

You Li¹, Qian Zhao, Ti Wang, Jie Liu, Junyan Li, Tao Li, Zhen Zeng, Guoyin Feng, Lin He, Yongyong Shi

Affiliation

¹ Bio-X Center and Affiliated Changning Mental Health Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China.

PMID: 20538345
DOI: 10.1016/j.psychres.2010.04.019

Abstract

We carried out an association study between GNB1L and three mental disorders (major depressive disorder, bipolar disorder, schizophrenia) in Chinese Han population. Among 1135 cases and 1135 controls, findings suggests that GNB1L is linked with bipolar disorder and schizophrenia and not with major depressive disorder.

MeSH terms

Adult
Bipolar Disorder / genetics
China / ethnology
Depressive Disorder, Major / genetics
Female
Gene Frequency
Genome-Wide Association Study / methods
Genotype
Humans
Intracellular Signaling Peptides and Proteins / genetics*
Male
Mental Disorders / classification
Mental Disorders / ethnology
Mental Disorders / genetics*
Polymorphism, Single Nucleotide / genetics*
Schizophrenia / genetics

Substances

GNB1L protein, human
Intracellular Signaling Peptides and Proteins