Morbimortality in octogenarian patients submitted to coronary artery bypass graft surgery

Arq Bras Cardiol. 2010 Jul;95(1):41-6. doi: 10.1590/s0066-782x2010005000071. Epub 2010 Jun 18.
[Article in English, Portuguese]

Abstract

Background: Given the progressive increase in longevity and the need of an increasingly elderly population to undergo myocardial revascularization surgery (MRS), it becomes necessary to know its risks and benefits.

Objective: To evaluate the in-hospital morbimortality of patients aged 80 and older submitted to MRS and identify its predictor variables.

Methods: A total of 140 consecutive cases were studied between January 2002 and December 2007. The patients' mean age was 82.5 +/- 2.2 years (range: 80-89) and 55.7% were males. In the sample,72.9% had arterial hypertension, 26.4% had diabetes, 65.7% presented severe lesion in three or more vessels and 28.6% presented a severe lesion in the left coronary trunk. An associated surgery was present in 35.7% of the cases, with aortic valve in 26.4% and mitral valve in 5.6%.

Results: The mortality rate was 14.3% (isolated MRS 10.0% vs 22.0% with associated procedure; p = 0.091) and the morbidity was 37.9% (isolated MRS 34.4% vs 44.0% with associated procedure; p = 0.35). The most frequent complications were low cardiac output (27.9%), renal dysfunction (10.0%) and prolonged ventilatory support (9.6%). At the bivariate analysis, the most important mortality predictors were sepsis (RR 10.2; 95%CI: 6.10-17.7), previous MRS (RR 8.06; 95%CI: 5.16-12.6), postoperative low cardiac output (RR 7.77; 95%CI: 3.03-19.9) and postoperative renal dysfunction (RR 7.36; 95%CI: 3.71-14.6). The morbidity predictors were extracorporeal circulation time > 120 min. (RR: 2.34; 95%CI: 1.62-3.38) and time of ischemia > 90 min. (RR: 2.29 95%CI: 1.56-3.37).

Conclusion: The MRS in octogenarians is associated with a higher morbimortality when compared to younger patients, which, however, does not prevent the procedure if the indication is justified by clinical condition.

MeSH terms

  • Age Factors
  • Aged, 80 and over
  • Coronary Artery Bypass / mortality*
  • Female
  • Hospital Mortality*
  • Humans
  • Male
  • Myocardial Infarction / mortality*
  • Myocardial Infarction / surgery
  • Prevalence
  • Retrospective Studies
  • Risk Factors