There was analyzed in detail a current state of diabetic foot syndrome (DFS) problem. In spite of that DFS constitutes the discrete nosological entity, it is not included into International Classification of the Diseases (ICD-10). The absence of classification of complicated DFS does not permit to elaborate protocols of the patients treatment standards and to determine real terms of their stationary treatment. Basing on analysis of the work experience of Purulent-septic center, owing hospital beds for the treatment of patients, suffering DFS, concerning diagnosis and treatment of more than 1500 patients with the DFS complications, the original classification of complicated DFS was presented by the authors, which is proposed for discussion in a wide round of specialists.