Abstract
Regulatory T cells (Treg) offer potential for improving long-term outcomes in cell and organ transplantation. The non-human primate model is a valuable resource for addressing issues concerning the transfer of Treg therapy to the clinic. Herein, we discuss the properties of non-human primate Treg and prospects for their evaluation in allotransplantation and xenotransplantation.
Publication types
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Editorial
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adoptive Transfer / methods
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Animals
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Antigens, CD / analysis
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Cell Division
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Flow Cytometry
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Humans
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Immunologic Memory
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Immunosuppressive Agents / therapeutic use
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Lymphocyte Activation
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Lymphocyte Depletion
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Macaca fascicularis
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Primates
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Rodentia
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T-Lymphocytes, Regulatory / cytology
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T-Lymphocytes, Regulatory / immunology
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T-Lymphocytes, Regulatory / physiology*
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T-Lymphocytes, Regulatory / transplantation*
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Transplantation, Heterologous / immunology*
Substances
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Antigens, CD
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Immunosuppressive Agents