Keeping the epidermal stem cell niche in shape

Ramiro Iglesias-Bartolome; J Silvio Gutkind

doi:10.1016/j.stem.2010.07.008

Keeping the epidermal stem cell niche in shape

Cell Stem Cell. 2010 Aug 6;7(2):143-5. doi: 10.1016/j.stem.2010.07.008.

Authors

Ramiro Iglesias-Bartolome¹, J Silvio Gutkind

Affiliation

¹ Oral and Pharyngeal Cancer Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892, USA.

PMID: 20682441
DOI: 10.1016/j.stem.2010.07.008

Abstract

Recently in Nature Cell Biology,Connelly et al. (2010) identified biomechanical sensing mechanisms that link the physical shape of the stem cell microenvironment to epithelial stem cell fate decisions. Ultimately, the integration of extrinsic and intrinsic signals controls stem cell self-renewal or differentiation.

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