Auto-immune spondylodiscitis associated with collagen induced arthritis in rats: high field MRI findings

Agents Actions Suppl. 1991:32:185-9. doi: 10.1007/978-3-0348-7405-2_25.

Abstract

The spinal involvement of the tail was studied in Wistar Furth rats immunized with bovine native type II collagen. Focal caudal autoimmune spondylodiscitis occurred 5 weeks after sensitization, as assessed histopathologically. High field Magnetic Resonance Imaging (MRI) was useful in depicting these caudal abnormalities that were related to juxta-diskal enthesitis. The occurrence of such inflammatory enthesopathies could serve as an experimental approach for physiopathological and therapeutical studies of spondylarthropathies.

MeSH terms

  • Animals
  • Arthritis, Experimental / complications
  • Arthritis, Experimental / diagnostic imaging
  • Arthritis, Experimental / pathology*
  • Autoimmune Diseases / diagnostic imaging
  • Autoimmune Diseases / pathology*
  • Collagen
  • Discitis / etiology
  • Discitis / pathology*
  • Female
  • Magnetic Resonance Imaging
  • Radiography
  • Rats
  • Rats, Inbred WF
  • Tail / diagnostic imaging
  • Tail / pathology

Substances

  • Collagen