[Screening of silent myocardial ischaemia by dobutamine stress echocardiography among type 2 diabetics at high cardiovascular risk in Senegal]

Ann Cardiol Angeiol (Paris). 2011 Apr;60(2):67-70. doi: 10.1016/j.ancard.2010.07.001. Epub 2010 Aug 1.
[Article in French]

Abstract

Introduction: Diabetes is a major risk factor for coronary artery disease witch may develop insidiously. Several non-invasive methods are used to detect silent myocardial ischaemia, especially in diabetic patients at high cardiovascular risk. We project to screen, by dobutamine stress echocardiography, silent myocardial ischaemia in type 2 diabetics in Senegal.

Methodology: We randomly recruited in hospital in Senegal type 2 diabetics aged at least 40 years and a dobutamine stress echocardiography was performed in those selected according to the French Society of Cardiology and the French Language Association for the Study of Diabetes and Metabolic Diseases.

Results: Dobutamine stress echocardiography was performed in 79 diabetics at high cardiovascular risk, including 56 women. The average age was 58.8±11.8 years. The exam was positive in 67.1% of cases (53/79), with a predominance of motion abnormalities in anterior territory (83%). Cardiovascular risk factors associated with positivity of test were microalbuminuria (p=0.0001), inactivity (p=0.0001), dyslipidemia (p=0.0002), arterial hypertension (p=0.001), smoking (0.003) and male sex (p=0.004).

Conclusion: In Africa, dobutamine stress echocardiography has the advantage of its accessibility and its feasibility. Early detection of silent myocardial ischaemia in diabetics at high risk could optimize their care.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Albuminuria / complications
  • Cardiotonic Agents*
  • Coronary Artery Disease / diagnostic imaging
  • Diabetes Complications / diagnostic imaging*
  • Diabetes Mellitus, Type 2 / complications*
  • Dobutamine*
  • Dyslipidemias / complications
  • Echocardiography, Stress*
  • Feasibility Studies
  • Female
  • Humans
  • Hypertension / complications
  • Life Style
  • Male
  • Mass Screening*
  • Middle Aged
  • Myocardial Ischemia / complications
  • Myocardial Ischemia / diagnostic imaging*
  • Predictive Value of Tests
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Senegal
  • Sensitivity and Specificity
  • Sex Distribution
  • Smoking / adverse effects

Substances

  • Cardiotonic Agents
  • Dobutamine