Modular blue fluorescent RNA sensors for label-free detection of target molecules

Mol Biosyst. 2010 Sep;6(9):1569-71. doi: 10.1039/c001230k. Epub 2010 Mar 12.

Abstract

A blue fluorescent RNA was applied to modular blue fluorescent RNA sensors, wherein a "recognition" event of the target molecule by the aptamer domain is transmitted through a "communication" module, to a "signaling" fluorescent RNA domain, which "lights up".

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Biosensing Techniques / methods*
  • Bisbenzimidazole / chemistry
  • Fluorescent Dyes / chemistry*
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • RNA / chemistry*

Substances

  • Fluorescent Dyes
  • RNA
  • Bisbenzimidazole