Efficient sonochemical synthesis of thiazolidinones from piperonilamine

Patrícia D Neuenfeldt; Auri R Duval; Bruna B Drawanz; Pauline F Rosales; Claudia R B Gomes; Claudio M P Pereira; Wilson Cunico

doi:10.1016/j.ultsonch.2010.07.008

Efficient sonochemical synthesis of thiazolidinones from piperonilamine

Ultrason Sonochem. 2011 Jan;18(1):65-7. doi: 10.1016/j.ultsonch.2010.07.008. Epub 2010 Jul 27.

Authors

Patrícia D Neuenfeldt¹, Auri R Duval, Bruna B Drawanz, Pauline F Rosales, Claudia R B Gomes, Claudio M P Pereira, Wilson Cunico

Affiliation

¹ Núcleo de Química Aplicada (NuQuiA), Departamento de Química Orgânica, Universidade Federal de Pelotas-UFPel, Campus Universitário s/no, 96010-900 Pelotas, RS, Brazil.

PMID: 20724206
DOI: 10.1016/j.ultsonch.2010.07.008

Abstract

An efficient multicomponent reaction of arenealdehydes, mercaptoacetic acid and piperonilamine under ultrasound irradiation to afford 2-aryl-3-(piperonylmethyl)-1,3-thiazolidin-4-ones is reported. Applying this methodology, eleven heterocycles were synthesized and isolated in good yields after short reaction times.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzodioxoles / chemistry*
Cyclization
Electrochemical Techniques*
Heterocyclic Compounds / chemical synthesis*
Heterocyclic Compounds / chemistry
Methylamines / chemistry*
Molecular Structure
Stereoisomerism
Thiazolidines / chemical synthesis*
Thiazolidines / chemistry
Ultrasonics*

Substances

Benzodioxoles
Heterocyclic Compounds
Methylamines
Thiazolidines
piperonilamine