Coronary artery disease: Percent stenosis in CAD--a flaw in current practice

K Lance Gould; Nils P Johnson

doi:10.1038/nrcardio.2010.119

Coronary artery disease: Percent stenosis in CAD--a flaw in current practice

Nat Rev Cardiol. 2010 Sep;7(9):482-4. doi: 10.1038/nrcardio.2010.119.

Authors

K Lance Gould¹, Nils P Johnson

Affiliation

¹ Weatherhead PET Imaging Center for Preventing and Reversing Atherosclerosis, University of Texas Medical School, 6431 Fannin, Houston, TX 77030, USA. k.lance.gould@uth.tmc.edu

PMID: 20725105
DOI: 10.1038/nrcardio.2010.119

Abstract

The optimum strategy to treat patients with coronary artery disease (CAD) has been under debate. New data show that revascularization guided by fractional flow measurements leads to better outcomes than revascularization guided by arteriography. we call for a paradigm shift in CAD care, with coronary flow measurements by PET as key to diagnosis and clinical decision-making.

MeSH terms

Angiography
Blood Flow Velocity
Coronary Artery Disease / diagnosis
Coronary Artery Disease / pathology
Coronary Artery Disease / therapy
Coronary Stenosis / diagnosis*
Coronary Stenosis / pathology
Coronary Stenosis / therapy
Health Status Indicators
Humans
Myocardial Reperfusion / methods*
Positron-Emission Tomography
Prognosis
Severity of Illness Index