The survival and sequelae of the very low birth weight (VLBW) newborns are reported. Two time-periods have been compared (1980-84 vs 1985-88) as well as two weight groups. (Lower than 1,000 vs 1,000-1,499). A total number of 205 VLBW were admitted, and 74 died. Only 72 were used to study morbidity and sequelae with a minimum follow-up of 12 months after correcting age. Those with a weight lower than 1,000 g have a greater motor impairment, (45.5 vs 16.4%), cognitive deficiency (55.5 vs 14.8%), myopia (27.3 vs 3.3%), neurosensorial deafness (27.3 vs 0%), and overall sequelae. During the period 1985-88, survival was 77.9% of the VLBW have any sequelae (12.5% major sequelae and 15.3% minor sequelae). A 36.4% of the newborns with a weight under 1,000 g have major sequelae comparing with the 8.2% in the others. Growth delay is closely related to neurologic sequelae.