Neonatal outcomes of Pierre Robin sequence: an institutional experience

Clin Pediatr (Phila). 2010 Dec;49(12):1117-22. doi: 10.1177/0009922810379040. Epub 2010 Sep 13.

Abstract

Objective: The aim of this study was to characterize the outcomes of one institute's experience regarding upper airway and feeding management in Pierre Robin sequence (PRS) neonates.

Study design: A retrospective review of 33 neonates was performed. Average daily weight gain for all patients and average length of stay for each group was calculated and the results were compared using Student's t test.

Result: Average daily weight gain was 16.5 g in the mandibular distraction osteogenesis (MDO) group (MDO; N = 12) and 5.6 g in the nonsurgical intervention (NSI) group (N = 18; P = .043). Average length of stay was longer in the MDO group (P = .01). In all, 67% of MDO patients were discharged with total PO (per os) feeds compared with 22% of NSI patients.

Conclusion: Neonates with PRS who do not require surgical airway intervention are more likely to require assisted feeding, have slower weight gain, and a shorter average hospital stay compared to neonates undergoing mandibular MDO.

Publication types

  • Comparative Study

MeSH terms

  • Enteral Nutrition
  • Female
  • Humans
  • Infant, Newborn
  • Length of Stay / statistics & numerical data*
  • Male
  • Mandible / abnormalities
  • Mandible / surgery*
  • Osteogenesis, Distraction / adverse effects*
  • Osteogenesis, Distraction / methods
  • Patient Discharge / statistics & numerical data*
  • Pierre Robin Syndrome / surgery*
  • Pierre Robin Syndrome / therapy
  • Retrospective Studies
  • Treatment Outcome
  • Weight Gain*