A myosin V inhibitor based on privileged chemical scaffolds

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8484-8. doi: 10.1002/anie.201004026.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Indoles / chemistry
  • Indoles / pharmacology
  • Kinetics
  • Mice
  • Myosin Type V / antagonists & inhibitors*
  • Myosin Type V / metabolism
  • Oxindoles
  • Pyrazoles / chemistry
  • Pyrazoles / pharmacology
  • Pyridines / chemistry
  • Pyridines / pharmacology
  • Pyrimidines / chemistry
  • Pyrimidines / pharmacology
  • Pyrroles / chemistry
  • Pyrroles / pharmacology
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors
  • Indoles
  • Oxindoles
  • Pyrazoles
  • Pyridines
  • Pyrimidines
  • Pyrroles
  • pyrazolopyridine
  • pyrrolopyrimidine
  • 2-oxindole
  • Myosin Type V