Design and discovery in the development of long-acting renin inhibitors

Biochem Soc Trans. 1990 Dec;18(6):1291-4. doi: 10.1042/bst0181291.
No abstract available

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biological Availability
  • Drug Design*
  • Macaca mulatta
  • Molecular Sequence Data
  • Oligopeptides / chemistry
  • Oligopeptides / pharmacokinetics
  • Oligopeptides / pharmacology
  • Renin / antagonists & inhibitors*
  • Structure-Activity Relationship

Substances

  • Oligopeptides
  • renin inhibitory peptide, statine
  • renin inhibitory peptide, 4-amino-5-cyclohexyl-3-hydroxypentanoic acid
  • Renin