Epimyoepithelial carcinoma (EMC) of salivary gland origin, primarily in the parotid gland, is a tumor in its own right and of low malignancy, usually occurring in women. Our patient is alive with her second recurrence, 16 years after the first surgical intervention. Immunohistochemical results suggest active involvement of myoepithelial and epithelial components of intercalated ducts in the histogenesis of this particular tumor.