Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device

M Marinacci; G Del Proposto; A Catapano; A S Ferraro; P Cerrone; A Lanti; L Uccioli; L Giurato; E D'Ambrogi; G Adorno; G Isacchi

doi:10.1016/j.transci.2010.07.013

Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device

Transfus Apher Sci. 2010 Oct;43(2):171-2. doi: 10.1016/j.transci.2010.07.013.

Authors

M Marinacci¹, G Del Proposto, A Catapano, A S Ferraro, P Cerrone, A Lanti, L Uccioli, L Giurato, E D'Ambrogi, G Adorno, G Isacchi

Affiliation

¹ Via del Padiglione 105, 00132 Rome, Italy. momixdoc@hotmail.com

PMID: 20926346
DOI: 10.1016/j.transci.2010.07.013

Abstract

There is evidence that platelets may be used locally as a source of growth factors that play a fundamental role in wound healing. From October 2008 to September 2009, at Tor Vergata Rome University Hospital, seven patients were enrolled in the study. All of these patients had ulcers with a extension over 3.5 cm(2). Four patients achieved a total recovery of the ulcers, while three experienced a reduction of the diameter of the ulcers. Our data are preliminary, but it is possible to suggest that recovery of the ulcers using the FIBRINET® system is related to platelet activation in the specific ulcer area.

MeSH terms

Aged
Blood Platelets / cytology*
Blood Pressure
Diabetic Foot / diagnosis*
Diabetic Foot / pathology
Equipment Design
Equipment and Supplies
Female
Fibrin / chemistry*
Flow Cytometry / methods
Humans
Male
Middle Aged
Platelet Activation
Wound Healing*

Substances

Fibrin