Aortic root reoperations after pulmonary autograft implantation

J Thorac Cardiovasc Surg. 2010 Dec;140(6 Suppl):S58-63; discussion S86-91. doi: 10.1016/j.jtcvs.2010.07.065.

Abstract

Objective: To report the results of aortic root reoperations after pulmonary autograft implantation.

Methods: All consecutive patients in our prospective Ross research database were selected for analysis, and additional information for patients requiring reoperation was obtained from the hospital records.

Results: From 1988 to 2009, 155 pulmonary autograft operations were performed. During this period, 41 patients required reoperation for aortic root dilatation and/or autograft valve insufficiency, in 8 patients combined with pulmonary allograft dysfunction. The freedom from autograft reoperation rate was 86% (standard error, 3.3%) after 10 years and 52% (standard error, 6.6%) after 15 years. The median interval to reoperation was 15.3 years. During reoperation, 39 patients underwent aortic root replacement (mechanical conduit, 31; stentless root, 2; allograft, 3; and valve sparing, 3), and 2 patients underwent valve replacement. In 8 patients this was combined with pulmonary allograft replacement. The technical difficulties encountered included bleeding at the sternal re-entry in 5 patients. No 30-day mortality occurred. The postoperative complications included reexploration for persistent blood loss in 3 patients and cerebrovascular accident in 3 patients. Two patients died during the follow-up period. The survival rate after reoperation was 94% (standard error, 4.1%) at 5 years.

Conclusions: An increasing number of patients requires reoperation after pulmonary autograft implantation. These reoperations can be done with very low mortality and morbidity and excellent follow-up results.

MeSH terms

  • Adolescent
  • Adult
  • Aortic Aneurysm / etiology
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / surgery*
  • Aortic Valve / surgery*
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Blood Vessel Prosthesis Implantation* / mortality
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Heart Valve Diseases / mortality
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / mortality
  • Humans
  • Infant
  • Infant, Newborn
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Netherlands
  • Proportional Hazards Models
  • Prospective Studies
  • Pulmonary Valve / transplantation*
  • Reoperation
  • Risk Assessment
  • Risk Factors
  • Survival Rate
  • Time Factors
  • Transplantation, Autologous
  • Treatment Outcome
  • Young Adult