Effect of concomitant opioid analgesics and oral sucrose during heel lancing

Early Hum Dev. 2011 Feb;87(2):147-9. doi: 10.1016/j.earlhumdev.2010.11.008. Epub 2010 Dec 8.

Abstract

A sub-analysis was conducted of data from a study of prolonged use of sucrose for hospitalized infants (N=50 infants) during heel lancing. Results showed that pain responses differed when opioid analgesics were administered concomitantly with sucrose (n=79 pain assessments), than when sucrose was administered alone (n=364 pain assessments).

Publication types

  • Clinical Trial

MeSH terms

  • Administration, Oral
  • Analgesics, Opioid / administration & dosage*
  • Crying
  • Drug Therapy, Combination / methods
  • Facial Expression
  • Heart Rate / physiology
  • Heel* / physiology
  • Humans
  • Infant, Newborn
  • Pain Measurement / methods*
  • Sucrose / administration & dosage*

Substances

  • Analgesics, Opioid
  • Sucrose