Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings

Dis Aquat Organ. 2010 Oct 26;92(1):83-8. doi: 10.3354/dao02273.

Abstract

A spontaneous seminoma in a 3 yr old male koi carp Cyprinus carpio L. is described. The animal, presenting a symmetric abdominal enlargement, showed a celomatic multinodular, white-yellowish and firm mass that infiltrated the liver and the intestine wall. Histologically, the neoplasm was non-encapsulated and poorly demarcated, showed invasive growth and was characterized by a lobular architecture, subdivided by abundant fibro-connective septa. Large necrotic and calcified areas together with small aggregates of residual spermatids were present. We diagnosed a classical seminoma with a diffuse pattern. Neoplastic cells cross-reacted with vimentin, placental alkaline phosphatase, and c-KIT. An immunohistochemical phenotypization of the tumor was performed to exclude other celomatic neoplasms and to compare this seminoma with those reported in mammals and humans.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Carps*
  • Fish Diseases / pathology*
  • Male
  • Seminoma / pathology
  • Seminoma / veterinary*
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / veterinary*