Can 'high-risk' human papillomaviruses (HPVs) be detected in human breast milk?

Acta Paediatr. 2011 May;100(5):705-7. doi: 10.1111/j.1651-2227.2010.02129.x. Epub 2011 Jan 14.

Abstract

Aim: Human papillomavirus (HPV) transmission via nonsexual modes in childhood has been proposed by several researchers. The aim of our study was to determine the presence of 'high-risk' HPV DNA in human breast milk.

Methods: Using polymerase chain reaction techniques, we evaluated the presence of HPV infection in human breast milk collected from 21 HPV-positive and 11 HPV-negative mothers.

Results: Of the 32 studied human milk specimens, no 'high-risk' HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 or 58 DNA was detected.

Conclusion: This preliminary case-control study indicates the absence of mucosal 'high-risk' HPV types in human breast milk.

MeSH terms

  • Adult
  • Alphapapillomavirus / genetics*
  • Case-Control Studies
  • DNA, Viral / isolation & purification*
  • Female
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical
  • Milk, Human / virology*
  • Papillomavirus Infections / transmission
  • Polymerase Chain Reaction
  • Risk Assessment
  • Young Adult

Substances

  • DNA, Viral