Effect of a monounsaturated diet vs. a polyunsaturated fatty acid-enriched diet on blood pressure in normotensive women and men

Eur J Clin Invest. 1990 Aug;20(4):463-9. doi: 10.1111/j.1365-2362.1990.tb01885.x.

Abstract

The effect on blood pressure of monounsaturated and (n-6)polyunsaturated fatty acids was studied under strict dietary control in normotensive subjects. For 17 days 31 women and 27 men received a control diet providing 19.3% of energy as saturated fat. Then subjects were randomized over two test diets: one diet provided 15.1% of energy from monounsaturated and 7.9% from polyunsaturated fatty acids ('mono diet'), and the other diet provided 10.8% from monounsaturated and 12.7% from polyunsaturated fatty acids ('poly diet'). Saturated fat intake was now 12.8% on both diets. Mean blood pressure at the end of the control period was 116/69 mmHg for the mono group and 117/73 mmHg for the poly group. After 5 weeks on the test diet, blood pressure was 115/67 mmHg for the mono group and 117/72 mmHg for the poly group (difference in changes between the two diet groups was not significant). These findings suggest that at a high fat intake, linoleic acid, when providing more than 7.9% of energy intake, does not influence blood pressure relative to oleic acid in normotensive women and men.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Pressure / drug effects*
  • Dietary Fats / pharmacology*
  • Eating
  • Fatty Acids, Monounsaturated / pharmacology*
  • Fatty Acids, Unsaturated / pharmacology*
  • Female
  • Humans
  • Linoleic Acid
  • Linoleic Acids / pharmacology
  • Male
  • Oleic Acid
  • Oleic Acids / pharmacology

Substances

  • Dietary Fats
  • Fatty Acids, Monounsaturated
  • Fatty Acids, Unsaturated
  • Linoleic Acids
  • Oleic Acids
  • Oleic Acid
  • Linoleic Acid