Affinity purification, biological characterization and serological evaluation of defined antigens from Mycobacterium tuberculosis

L Ljungqvist; A B Andersen; P Andersen; K Hasløv; A Worsaae; J Bennedsen; I Heron

Affinity purification, biological characterization and serological evaluation of defined antigens from Mycobacterium tuberculosis

Trop Med Parasitol. 1990 Sep;41(3):333-5.

Authors

L Ljungqvist¹, A B Andersen, P Andersen, K Hasløv, A Worsaae, J Bennedsen, I Heron

Affiliation

¹ Mycobacteria Department, Statens Seruminstitut, Copenhagen, Denmark.

PMID: 2123997

Abstract

Nine mycobacterial antigens have been purified by affinity chromatography using monoclonal antibodies (m. abs) as immunosorbent. The importance of the individual antigens have been evaluated by different immunological methods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antibodies, Bacterial / analysis*
Antibodies, Monoclonal / immunology*
Antigens, Bacterial / immunology
Antigens, Bacterial / isolation & purification*
Chromatography, Affinity
Enzyme-Linked Immunosorbent Assay
Guinea Pigs
Humans
Immune Sera / immunology
Lymphocyte Activation
Mice
Mice, Inbred Strains
Mycobacterium tuberculosis / immunology*
T-Lymphocytes / immunology
Tuberculosis, Pulmonary / diagnosis*
Tuberculosis, Pulmonary / immunology

Substances

Antibodies, Bacterial
Antibodies, Monoclonal
Antigens, Bacterial
Immune Sera