[Analysis of neutralized antibody level of the poliomyelitis in healthy population in Fujian province]

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2010 Oct;24(5):352-4.
[Article in Chinese]

Abstract

Objective: To understand the neutralized antibody level of the poliomyelitis among healthy people and provide scientific evidence for the immunization strategy since routine and intensified immunization with oral polio vaccine (OPV) in Fujian province.

Methods: The poliomyelitis antibody level of healthy people were detected by neutralization test of the micro cells.

Results: The neutralizing antibody positive rates were 99.0%, 99.3%, 97.5% and GMTs were 1:79.1, 1:31.2, 1:24.7 for polio I, II, III respectively in 400 serum specimens from 1-59 years old. GMTs present a trend of decreasing as age's increasing.

Conclusion: A protective barrier had been built against poliomyelitis in healthy people in Fujian province through routine and intensified immunization with OPV.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Neutralizing / blood
  • Antibodies, Neutralizing / immunology*
  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology
  • Child
  • Child, Preschool
  • China
  • Female
  • Health Status
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Poliomyelitis / immunology*
  • Poliomyelitis / prevention & control
  • Poliomyelitis / virology
  • Poliovirus Vaccine, Oral / administration & dosage
  • Poliovirus Vaccine, Oral / immunology
  • Population Surveillance*
  • Vaccination
  • Young Adult

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral
  • Poliovirus Vaccine, Oral