Roles of G proteins and G protein subunits in signal transduction

R Iyengar; L Birnbaumer

Roles of G proteins and G protein subunits in signal transduction

Lymphokine Res. 1990 Winter;9(4):533-7.

Authors

R Iyengar¹, L Birnbaumer

Affiliation

¹ Department of Pharmacology, Mount Sinai School of Medicine, New York, NY 10029.

PMID: 2128642

Abstract

General features of signal transduction by G proteins are described. Recent results on roles of beta gamma dimers, kinetic properties of Gi alpha subunits, structural diversity of Go alpha subunits and possible functions of the Go protein as a stimulator of phospholipase C activity are discussed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Amino Acid Sequence
Animals
Biopolymers
GTP-Binding Proteins / physiology*
Molecular Sequence Data
Signal Transduction / physiology*
Xenopus laevis

Substances

Biopolymers
GTP-Binding Proteins