[A serious "acetaldehyde syndrome" compounded by dopamine]

Ann Fr Anesth Reanim. 2011 Feb;30(2):150-2. doi: 10.1016/j.annfar.2010.11.022. Epub 2011 Feb 2.
[Article in French]

Abstract

Disulfiram is commonly used in the treatment of alcohol dependence. It induces aversive symptoms after alcohol ingestion: the "acetaldehyde syndrome". Most often "acetaldehyde syndrome" is moderate but severe life-threatening symptoms may occur in specific circumstances. We report the case of a serious "acetaldehyde syndrome" with shock compounded by the initial administration of dopamine. Discussion clarifies the pathophysiology and develops the therapeutic management.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acetaldehyde / adverse effects*
  • Alcohol Deterrents / adverse effects*
  • Alcoholic Intoxication / complications
  • Alcoholism / complications
  • Alcoholism / drug therapy
  • Anti-Anxiety Agents / therapeutic use
  • Antidepressive Agents / therapeutic use
  • Bipolar Disorder / complications
  • Bipolar Disorder / drug therapy
  • Cardiotonic Agents / adverse effects*
  • Central Nervous System Depressants / adverse effects
  • Disulfiram / adverse effects*
  • Dopamine / adverse effects*
  • Electrocardiography
  • Ethanol / adverse effects
  • Humans
  • Hypokalemia / chemically induced
  • Hypokalemia / therapy
  • Male
  • Middle Aged

Substances

  • Alcohol Deterrents
  • Anti-Anxiety Agents
  • Antidepressive Agents
  • Cardiotonic Agents
  • Central Nervous System Depressants
  • Ethanol
  • Acetaldehyde
  • Disulfiram
  • Dopamine