Single-center experience of surgical and endovascular treatment of ruptured intracranial aneurysms

AJNR Am J Neuroradiol. 2011 Mar;32(3):570-5. doi: 10.3174/ajnr.A2326. Epub 2011 Feb 24.

Abstract

Background and purpose: ISAT provided valuable data on patient outcome after endovascular coiling and surgical clipping of ruptured aneurysms. The purpose of this study was to retrospectively review the ≥1-year outcome (in terms of survival, independence, and rebleeding) of patients who were treated in a routine clinical setting.

Materials and methods: Records of patients presenting with an SAH from a ruptured aneurysm between 2000 and 2008 were reviewed. The 403 patients who met the inclusion criteria harbored 443 treated aneurysms; 173 were managed surgically and 230 by endovascular means. Mean clinical follow-up was 33.9 months (range, 12-106 months).

Results: The pretreatment clinical condition according to the HH was significantly better in the surgically treated patients (P = .018). Death occurred in 11.6% after surgery and in 17.4% after endovascular treatment (P = .104). Of the surviving patients in the surgical and endovascular groups, 80.3% and 87.2%, respectively, were able to live independently with grades 0-2 on the mRS (P = .084). Complete aneurysm occlusion was achieved significantly more often after surgical treatment (P < .001). Rebleeding occurred in 3.1% and 2.3% of the patients after surgical treatment and endovascular coiling, respectively. The occurrence of a residual aneurysm at the end of a coiling procedure was significantly related to the frequency of rebleeding (P = .007).

Conclusions: The management of patients with intracranial aneurysms in a routine clinical setting shows good and comparable rates of mortality and independence. Coiling results in lower rates of complete aneurysm occlusion. Postcoiling angiography showing a residual aneurysm is a good predictor of the risk of rebleeding.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aneurysm, Ruptured / epidemiology*
  • Embolization, Therapeutic / statistics & numerical data*
  • Female
  • Humans
  • Intracranial Aneurysm / epidemiology*
  • Intracranial Aneurysm / surgery*
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Neurosurgical Procedures / statistics & numerical data*
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Stents / statistics & numerical data*
  • Young Adult