Effect of geometric variations on pressure loss for a model bifurcation of the human lung airway

J Biomech. 2011 Apr 7;44(6):1196-9. doi: 10.1016/j.jbiomech.2011.02.011. Epub 2011 Feb 26.

Abstract

Characteristics of pressure loss (ΔP) in human lung airways were numerically investigated using a realistic model bifurcation. Flow equations were numerically solved for the steady inspiratory condition with the tube length, the branching angle and flow velocity being varied over a wide range. In general, the ΔP coefficient K showed a power-law dependence on Reynolds number (Re) and length-to-diameter ratio with a different exponent for Re≥100 than for Re<100. The effect of different branching angles on pressure loss was very weak in the smooth-branching airways.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Lung / anatomy & histology
  • Lung / physiology*
  • Models, Biological*
  • Pressure
  • Respiratory Mechanics / physiology*
  • Respiratory Rate / physiology*