Abstract
A bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. Random mutagenesis of this phage rendered a bacteriophage able to kill 99% of the bacteria within a biofilm. This is the first report of a biocontrol experiment against A. actinomycetemcomitans.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Bacteriolysis*
-
Bacteriophages / drug effects
-
Bacteriophages / growth & development*
-
Bacteriophages / isolation & purification*
-
Biofilms / growth & development*
-
Mutagenesis
-
Mutagens / metabolism
-
Pasteurellaceae / growth & development*
-
Pasteurellaceae / virology*
-
Pest Control, Biological / methods