Parsing out the complexity of RAF inhibitor resistance

Pigment Cell Melanoma Res. 2011 Apr;24(2):361-5. doi: 10.1111/j.1755-148X.2010.00824.x. Epub 2011 Jan 12.
No abstract available

MeSH terms

  • Drug Resistance, Neoplasm*
  • Extracellular Signal-Regulated MAP Kinases / genetics
  • Extracellular Signal-Regulated MAP Kinases / metabolism
  • Humans
  • MAP Kinase Signaling System / physiology
  • Melanoma / genetics
  • Melanoma / pathology
  • Melanoma / therapy
  • Proto-Oncogene Proteins B-raf / antagonists & inhibitors*
  • Proto-Oncogene Proteins B-raf / genetics*
  • Signal Transduction / physiology
  • Skin Neoplasms / genetics
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy
  • raf Kinases / antagonists & inhibitors*
  • raf Kinases / genetics

Substances

  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf
  • raf Kinases
  • Extracellular Signal-Regulated MAP Kinases