DNA methylation and chromatin structure: a view from below

Trends Biochem Sci. 1990 Mar;15(3):103-7. doi: 10.1016/0968-0004(90)90193-f.

Abstract

An understanding of the function and control of DNA methylation in eukaryotes has been elusive. Studies of Neurospora crassa have led to a model that accounts for the chromosomal distribution of methylation and suggests a basic function for DNA methylation in eukaryotes.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Chromatin*
  • DNA / metabolism*
  • Eukaryotic Cells / metabolism
  • Methylation
  • Models, Genetic
  • Molecular Structure
  • Neurospora crassa / genetics
  • Prokaryotic Cells / metabolism

Substances

  • Chromatin
  • DNA