Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia

J Gen Virol. 2011 Jul;92(Pt 7):1676-1687. doi: 10.1099/vir.0.028308-0. Epub 2011 Mar 14.

Abstract

Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relationship of LEAV to other orthobunyavirus species. Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Anopheles / virology*
  • Australia
  • Genome, Viral
  • Genomics
  • Molecular Sequence Data
  • Orthobunyavirus / classification*
  • Orthobunyavirus / genetics*
  • Orthobunyavirus / isolation & purification
  • Phylogeny*

Associated data

  • GENBANK/HM627176
  • GENBANK/HM627177
  • GENBANK/HM627178