Cerebral sinus thrombosis following IV immunoglobulin therapy of immune thrombocytopenia purpura

Pediatr Blood Cancer. 2011 Jul 15;57(1):157-9. doi: 10.1002/pbc.22968. Epub 2011 Mar 28.

Abstract

We present a pediatric patient treated with high dose intravenous immunoglobulin (IVIG) for acute immune thrombocytopenic purpura (ITP), who developed cerebral sinus thrombosis in the absence of any identifiable hypercoagulable state. This report describes the successful management of this rare complication in this challenging setting. This report shows IVIG induced cerebral sinus thrombosis in ITP.

MeSH terms

  • Child
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage*
  • Immunoglobulins, Intravenous / adverse effects*
  • Male
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Sinus Thrombosis, Intracranial / chemically induced*
  • Sinus Thrombosis, Intracranial / therapy*

Substances

  • Immunoglobulins, Intravenous