[Stimulatory effect of the cord blood fraction below 5 kDa and "Actovegin" on the growth of continuous cell lines]

Tsitologiia. 2011;53(2):135-41.
[Article in Russian]

Abstract

The influence of the cattle cord blood fraction with molecular weight of components below 5 kDa on adhesive and proliferative properties of continuous cell lines BHK-21 clone q3/04 and PK-15-IECVM was investigated in comparison with the preparation "Actovegin". It was shown that adding this fraction as well as "Actovegin" to growth media did not affect the efficiency of culture attachment, promoted culture spreading, improved cell morphology and stimulated mitotic activity of the cultures. The efficiency of the cord blood fraction below 5 kDa estimated by the induces studied was found to be higher than the "Actovegin" efficiency when cells being cultivated in the media different contents of blood serum.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Cattle
  • Cell Adhesion / drug effects
  • Cell Line
  • Cell Proliferation / drug effects*
  • Cricetinae
  • Fetal Blood*
  • Heme / analogs & derivatives*
  • Heme / pharmacology

Substances

  • Antioxidants
  • Heme
  • Actovegin