Anterior cruciate ligament reconstruction is the sixth most common procedure performed by orthopaedic surgeons. The goals of the procedure are to restore knee stability and patient function. These goals are dependent on proper graft positioning and incorporation. Anterior cruciate ligament reconstruction involves a technically complicated series of steps, all of which affect graft healing and clinical outcome. A wide variety of graft choices and surgical techniques are currently available for use. It is important for orthopaedic surgeons performing anterior cruciate ligament reconstructions to be aware of the indications for graft selection, techniques for correct graft placement, and the biologic implications related to these factors.